Ketamine for Depression
How Does Ketamine Help With Depression?
We Can Help You Take Back Control
At NeuroRelief™, we use evidence-based approaches to patient care. Our clients achieve amazing results, gaining newfound relief, confidence and empowerment.
Ketamine infusion treatment for depression gives patients the fastest results of any known therapy! At NeuroRelief™, our patients see up to 83% success rates, with clients reporting AT LEAST 50% improvement in their symptoms. No more waiting for weeks to see results!
The NeuroRelief™ Difference: Treating the Whole Individual
At NeuroRelief™, every treatment plan for depression includes multiple, integrated components. To assist our unique clients in achieving their personal growth and treatment goals Dr. Harris, and our clinical team, incorporate several, synergistic approaches to address different facets of each person’s needs.
This detailed tailoring of treatment, coaching, and support allows clients to surpass even their own dreams of success and relief! Each treatment day consists of one-on-one emotional integration sessions, before and after each ketamine infusion.
Every NeuroRelief™ ketamine infusion program includes five(5) 1-hour, one-on-one integration therapy sessions with your personal Certified Integration and Recovery Coach between treatment days.
We incorporate cognitive behavior (CBT) learning and mindfulness training into every day of a client’s journey, to help them learn how to maintain the gains they achieve, for the long-term.
Our Medical Director, Dr. Harris, is amazingly accessible, 24/7, via text, email, and phone, to be contacted directly by each and every one of our clients. This unprecedented level of access to clinical and emotional support empowers our clients to maximize their successes and learn how to maintain them!
We work closely with each person’s existing mental health professional to become an important tool in a multi-faceted treatment approach. We look forward to providing the highest level of service to our clients.
How Does Ketamine Treat Depression?
Ketamine acts differently from other medications such as SSRIs, tricyclics, MAOI inhibitors, benzodiazepines, and other antidepressant or anti-anxiety medications. Ketamine infusions result in the structural re-wiring of neural pathways, not just a superficial band-aid.
- Ketamine allows our brains the ability to “reboot” and structurally repair the connections between nerve cells, called synapses. Mood disorders can disrupt these healthy connections and degrade our brains’ ability to repair them.
- Ketamine is an NMDA receptor antagonist. This action decreases the GABA inhibition of glutamate synapses, allowing them to wake back up. This then increases our ability to feel reward, and a sense of well-being, from daily stimuli.
- Ketamine increases our brains natural production of BDNF (brain-derived neurotrophic factor). BDNF is crucial enzyme that identifies and repairs maladaptive synapses, leading to regrowth and improved balancing of our mood
- Ketamine re-sensitizes ion-gated Calcium channels at these synapses, and increases the likelihood for synapses such as glutamate, serotonin and dopamine to fire, and increases the frequency at which they do fire. This is a great thing. It gives us more “bang-for-our-buck” reward from healthy, comforting stimuli that are all around us
- Ketamine Increases “Neuroplasticity” of nerve synapses. This allows repair and regrowth into healthier signaling paradigms, resulting in improved mood and coping skills.
- Ketamine allows for psychological healing of deep emotional conflicts. Our subconscious (which is our best friend and an infinitely wise processing system) can finally seek to safely process and resolve these conflicts, on our behalf.
- Ketamine can reset the “default mode network” of our brain. MRI data suggest that this network is where many maladaptive thought patterns and ruminations are stored. Inhibiting and resetting the patterns of these areas of the brain gives us the opportunity to rebuild a healthier relationship between ourselves and the beautiful world around us.
- **** There are no long-term negative side-effects from ketamine infusion therapy. It also has no physiologic dependency. With a 60-year safety profile, this is an extremely comforting record compared to many other treatment modalities
The Benefits of Ketamine: Before & After
Before Ketamine
- A person suffering from depression cannot escape their inner cycles of negative thought and self-judgement.
- Like a character in a movie, they feel trapped in the narrative and do not feel enabled to alter the course of the script.
- Depressed individuals feel like their energy is always sapped by the inability to disconnected from cyclical negative thought patterns. It is very difficult to gain willful control or to detach from feelings of hopelessness or low self worth.
After Ketamine
- Our clients are able to dissociate from their own movie, to examine their thoughts and state of being as an impartial observer of their own life’s journey.
- Patients feel empowered to calmly, and objectively, process information and thoughts; and without the rush of secondary anxieties, negative rumination, or doubt.
- The Ketamine experience gives each individual the opportunity to self-examine in a euphoric, safe place; to re-work their thought processes in a space that is filled with calm, wellbeing and relief.
Why do NON-Ketamine Depression Drugs & Treatments Fail?
Treating depression can be very difficult, even with the aid of many commonly prescribed medications. Many individuals feel like test-subjects, bouncing from one drug to the next, desperate for relief, but without receiving it.
Patients suffering from depression have likely been previously treated with one or more SSRI drugs such as Paxil, Luvox, Wellbutrin, Zoloft, and Lexapro, or SNRI drugs such as Effexor, Cymbalta, or Pristiq.
However, up to 50% of these patients may not experience true relief! What patients often DO experience, IMMEDIATELY, are debilitating side effects such as weight gain, nausea, loss of sex-drive, insomnia, chronic fatigue, dizziness, and blurred vision.
Some people may actually experience INCREASED suicidal thoughts from these frequently prescribed drugs. In addition, these medications usually take up to 6 weeks to show any positive effects, while the negative side effects can start immediately.
You Are "NOT" Alone In This Battle
Over 350 million individuals suffer from depression worldwide. According to the US National Institute of Mental Health, tens of millions of Americans, up to 17% of individuals, may experience disabling depression at some point in time. Additionally, each year, almost 5,000 youths lose their lives to depression, the third leading cause of death among ages 10-24
We Understand Your Struggle
Symptoms of Depression can often be overwhelming, and many people feel isolated and suffer alone with this condition. People feel that others will not understand their struggle, that they will be refused help or ridiculed. Unfortunately, all too many patients may eventually lose their battle, with terrible consequences.
Experts believe that much of depression is due to how certain nerve pathways, the circuits in your brain, send information, and may not be working properly. Specialized imaging scans show that the parts of your brain involved in mood, thinking, sleep, appetite, and behavior look predictably, and consistently, different when you’re depressed. With IV Ketamine therapy, many of these brain regions show dramatically improved activity after treatment!
At NeuroRelief™, we use evidence-based approaches to patient care. Our clients achieve amazing results, gaining newfound relief, confidence and empowerment. We work closely with each person’s existing mental health professional to become an important tool in a multi-faceted treatment approach. We can also assist in arranging referrals to one of our amazing colleagues. We look forward to providing the highest level of service to our clients.
Customized Protocols for Each Individual Client
1.5 to 2-hour one-on-on, pre-treatment consultation with the physician. (On your first treatment day). This is a wonderful opportunity for the physician that is leading your care to learn more about your individual needs and goals. This valuable time let’s your doctor learn how to best tailor the therapeutic approach to you, specifically, and to be the best guide possible through your journey of growth and healing
– Pre-treatment coaching/integration session
– 60 minutes of customized ketamine infusion (adjusted in real-time to optimize each client’s experience to their unique neurology, psychology, personality, physiology, and tolerance levels
– Recovery time (varies per client but every client is welcomed to stay in their relaxing treatment suite for as long as they like – you will NEVER be asked to leave to make room for another patient)
– Post-infusion integration session with Dr. Harris
– CBT (cognitive behavior technique) and Mindfulness training on how to increase the client’s benefit though at-home daily exercises.
– 24/7 direct contact via text/phone/email to your treating physician.
**** Emotional Coaching is provided, in the clinic, and also via 5 hours of live, one-on-one Zoom sessions with your own personal Certified Integration & Recovery Coach.
1.5 to 2-hour one-on-on, pre-treatment consultation with the physician. (On your first treatment day). This is a wonderful opportunity for the physician that is leading your care to learn more about your individual needs and goals. This valuable time let’s your doctor learn how to best tailor the therapeutic approach to you, specifically, and to be the best guide possible through your journey of growth and healing
– Pre-treatment coaching/integration session
– 120 minutes of customized ketamine infusion (adjusted in real-time to optimize each client’s experience to their unique neurology, psychology, personality, physiology, and tolerance levels
– Recovery time (varies per client but every client is welcomed to stay in their relaxing treatment suite for as long as they like – you will NEVER be asked to leave to make room for another patient)
– Post-infusion integration session with Dr. Harris
– CBT (cognitive behavior technique) and Mindfulness training on how to increase the client’s benefit though at-home daily exercises.
– 24/7 direct contact via text/phone/email to your treating physician.
**** Emotional Coaching is provided, in the clinic, and also via 5 hours of live, one-on-one Zoom sessions with your personal Certified Integration & Recovery Coach.
***Based on clinical experience
This longer infusion time provides additional increases in our brains own production of Brain-derived neurotrophic factor (BDNF). This improves the likelihood that our brain/body will adopt a new way of doing business for us, and not shrug off the treatment as an “outlier.” For clients that fall into one of the following categories, a higher boost in BDNF production (from a 2-hour infusion time) will likely achieve a significantly improved benefit vs. the 1-hour option:
o A history of suffering from mood related struggles for longer than 7-8 years
- The process of experiencing depression, anxiety, or PTSD creates anatomical damages to our neurology, and this makes it harder to reverse, the longer that these situations have lasted for. Ketamine can overcome this, and re-build lost neural connections. However, those with longer histories of mood struggles can benefit from a longer infusion time, to reach the same end-goal as folks with a shorter history of such struggles
o A history of taking antidepressant or anti-anxiety medications for longer than 5 years
- While many medications may benefit clients, for different reasons, we now believe that there is some cost associated with longer-term use. For example, with an SSRI (Zoloft, Prozac, Lexapro, etc.) the increased release of serotonin (associated with improved mood) can eventually be counteracted by our own brain. Our own neurology can see this change as a foreign influence that it needs to be balanced back to baseline. As such, it can take away post-synaptic receptors for neurotransmitters such as serotonin, dopamine, norepinephrine, glutamate, etc., and can result in feeling diminishing returns. In other words, without increasing doses or adding secondary medications, we can lose the “bang-for-our-buck” that we could receive from the satisfying and fulfilling stimuli that exist all around us. We can end up having less of these good receptors than we started with before taking these medications. In the abovementioned situation, a longer infusion time is recommended, to overcome this deficit, and to rebuild these lost receptors, giving us back our zest for living each day to its fullest.
o A history of alcohol or drug abuse (including prescription opiates/benzodiazepines) in the past 7-8 years
- Drugs and alcohol can desensitize receptors in the reward centers of our brain. It can also lead to increasing need for these substances to even feel “normal.” This is called dependency. While many people’s struggles can understandably lead to increased use of drugs/alcohol, it does set us backwards, in the long-term, in our ability to experience the beautiful, normal stimuli of each day.
- Ketamine can reset our reward instincts to regain the “bang-for-our-buck” from healthy stimuli, and we actually use ketamine to assist those struggling with alcohol or drug abuse in regaining their joy of daily life
- Ketamine also can reset the “demand” for these substances to overcome dependency need.
- 2-hour infusion time is recommended in order to overcome some of these neurologic deficits associate with substance abuse, and to give that individual that same benefits as other folks who may not have the same history.
o A 2-hour protocol can be superior for clients that may take a little longer to “let go.”
- Ketamine infusion is a beautifully transcendent experience but is a new process for most people. Once we feel comfortable, and can gain trust for this process, the ketamine journey opens, even further, into a wonderful liberation from our normal constraints. We believe that this “release point” actually signals the start of the therapeutic benefit. We each reach this level of acceptance at different rates, and we want our clients to achieve maximal benefit for themselves.
- If we have more hypervigilance, or a harder time being able to relax into a new situation, then a longer infusion time is recommended. This is to ensure that each person gets the maximum time, after “release”, that our brains are experiencing this new signal of freedom, warmth, comfort, and connection. This is the signal that we want our mind to learn from, and to begin to re-program and adapt to.
- Neuroscientists often call the duration of maximal neural signaling the “veracity.” This longer veracity improves the likelihood that our neurology and psyche will accept and adopt this improved means of processing data and stimuli, and to start to rewire for our benefit. This regrowth translates into a more joyful and connected relationship to the world around us, when go back into our daily life.
Can I Afford Ketamine Infusion Therapy?
Ketamine treatment plans are very individualized and there are several different protocols, just for depression. Through detailed phone consultation and intake with Dr. Harris, we support each client in making the choice of protocol that is perfect for them. We can share the differences in pricing of these different protocols during our first phone consultation.
At NeuroRelief™, the initial treatment plan we recommend for new clients is to come in for 6 treatment days over a 2-3 week period of time. This is the latest medical consensus of best initial practices for best initial results, called the Stabilization Protocol.
Please see our Affordability page for detailed information on our 15-month interest-free financing program and our robust superbill reimbursement services.
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