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Ketamine News & Research

Ketamine In The News

Featured Article

Healing With Ketamine & Psychdelics

It’s said that science progresses “one gravestone at a time,” since major changes in theoretical perspective usually require a new generation or more to take hold.

Psychiatry, in contrast, is in the midst of a massive shift: We’re experiencing a veritable psychedelic revolution, as drugs like MDMA, psilocybin, and ketamine offer new hope for treating severe mental anguish.

News Articles

Ketamine reverses neural changes underlying depression-related behaviors

Ketamine may rebuild broken brain synapses, according to new research

'Nothing less than transformational:' Ketamine brings relief to people with severe depression

How Ketamine Turbo Boosts Brain Compost to Improve Your Mood

Experience of the use of Ketamine to manage opioid withdrawal in an addicted woman: a case report

I tried ketamine to treat my depression. Within a day, I felt relief.

Ketamine Relieves Depression By Restoring Brain Connections

Australia’s largest trial of ketamine to treat depression begins

How Ketamine Infusions Saved My Life

Ketamine infusions may be helpful in central sensitization pain syndromes

Do IV drip bars really give you an immunity boost? I tried it and this is what happened.

Listening to Ketamine

Scientific Research

Addiction

Anxiety

Bipolar

Chronic and Neuropathic Pain

Depression

Migraines

Obsessive-Compulsive Disorders — OCD

Post-Traumatic Stress Disorder — PTSD

Suicidality

Clinical Trials

Ketamine as a novel treatment for major depressive disorder and bipolar depression: a systematic review and quantitative meta-analysis

Ellen E. Lee, M.D., Megan P. Della Selva, M.D., Anson Liu, M.D., Seth Himelhoch, M.D., M.P.H.
General Hospital Psychiatry, Published: 8 January 2015

Ketamine as a rapid-acting agent for suicidal ideation: A meta-analysis

Francesco Bartoli, Ilaria Riboldi, Cristina Crocamoa, Carmen Di Britaa, Massimo Clerici, Giuseppe Carràa
Neuroscience and Biobehavioral Reviews, Published: 23 March 2017

Efficacy of Ketamine in Bipolar Depression: Systematic Review and Meta-analysis

Ajay K. Parsaik, MD, MS, Balwinder Singh, MD, MS, Darrow Khosh-Chashm, MD, Soniya S. Mascarenhas, RN
Journal of Psychiatric Practice, Published: November 2015

Ketamine as a Fast Acting Antidepressant: Current Knowledge and Open Questions

Giacomo Salvadore & Jaskaran B. Singh
CNS Neuroscience & Therapeutics, Published: 18 February 2013

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

Carlos A. Zarate, Jr, MD; Jaskaran B. Singh, MD; Paul J. Carlson, MD; Nancy E. Brutsche, MSN; Rezvan Ameli, PhD; David A. Luckenbaugh, MA; Dennis S. Charney, MD; Husseini K. Manji, MD, FRCPC
Arch Gen Psychiatry, Published: August 2006

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic

John H. Krystal, Chadi G. Abdallah, Lynette A. Averill, Benjamin Kelmendi, Ilan Harpaz-Rotem, Gerard Sanacora, Steven M. Southwick, and Ronald S. Duman
Curr Psychiatry Rep, Published: 18 April 2018

Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder A Randomized Clinical Trial

JAdriana Feder, MD; Michael K. Parides, PhD; James W. Murrough, MD; Andrew M. Perez, MD; Julia E. Morgan, BA; Shireen Saxena, MScPH; Katherine Kirkwood, MS; Marije aan het Rot, PhD; Kyle A. B. Lapidus, MD, PhD; Le-Ben Wan, MD, PhD; Dan Iosifescu, MD; Dennis S. Charney, MD
JAMA Psychiatry, Published: 16 April 2014

Ketamine’s dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders

Andrew Gray, Neil Mcnaughton
Journal of Psychopharmacology, Published: April 2017

Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients

Thomas Graven-Nielsena, Sally Aspegren Kendallb, Karl G. Henriksson, Mats Bengtssone, Jan SoÈrensen, Anders Johnso, BjoÈrn Gerdle, Lars Arendt-Nielsen
Elsevier Science B.V, Published: 29 November 1999

Ketamine and Peripheral Inflammation

JAdriana Feder, MD; Michael K. Parides, PhD; James W. Murrough, MD; Andrew M. Perez, MD; Julia E. Morgan, BA; Shireen Saxena, MScPH; Katherine Kirkwood, MS; Marije aan het Rot, PhD; Kyle A. B. Lapidus, MD, PhD; Le-Ben Wan, MD, PhD; Dan Iosifescu, MD; Dennis S. Charney, MD
JAMA Psychiatry, Published: 16 April 2014

Outpatient intravenous ketamine for the treatment of complex regional pain syndrome: A double-blind placebo controlled study

Robert J. Schwartzman, Guillermo M. Alexander, John R. Grothusen, Terry Paylor, Erin Reichenberger, Marielle Perreault
PAIN, Published: 18 August 2009

Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1

Marnix J. Sigtermans, Jacobus J. van Hilten, Martin C.R. Bauer, M. Sesmu Arbous, Johan Marinus, Elise Y. Sarton, Albert Dahan
PAIN, Published: 18 June 2009

Intravenous ketamine for subacute treatment of refractory chronic migraine: a case series

Clinton Lauritsen, Santiago Mazuera, Richard B. Lipton and Sait Ashina
The Journal of Headache and Pain, Published: 2016

Glutamate and Its Receptors as Therapeutic Targets for Migraine

Jan Hoffmann, Andrew Charles The American Society for Experimental Neuro
Therapeutics, Published: 5 March 2018

Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review

Jennifer L. Jones, Camilo F. Mateus, Robert J. Malcolm, Kathleen T. Brady, and Sudie E. Back
frontiers in Psychiatry, Published: 24 July 2018

Ketamine for the treatment of addiction: evidence and potential mechanisms

Ivan Ezquerra-Romano, W. Lawn, E. Krupitsky, C.J.A. Morgan
Elsevier, Published: 12 January 2018

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